Using Bloglines was fairly easy. I tried some of their suggestions for feeds along with 2.0 suggestions. It would be really easy to waste a lot of time playing w/this! I deleated some of the feeds. On a personal level I subscribe to Google alerts and several sites send me emails to keep me up to date. I want to check to see which is most time efficient, email alerts or RSS.
In a library setting it could help staff stay up to date on professional issues and provide an informal way to update or train new skills.
I did try Google reader and MSN Feeds (less time consuming to set up and use, but not as appealing to the eye or as much "fun" as Google or Bloglines).